1. Improving primary care for Aboriginal mothers and babies in the Kimberley region of Western Australia: a population and region based cluster randomised trial driven by local health service providers $1,969,771
2. Improving access to primary care for Aboriginal babies in Western Australia. The ‘Stork’ population based cluster randomised trial. $1,250,992
Effect of anti-IgE antibody on immune system responses and short-term outcome in acute asthma in children $547,648
Comparing pneumococcal vaccines in a high risk population: a randomised controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea $1,009,610
Evaluation of Haemophilus haemolyticus as a preventative therapy for NTHi disease $431,830
Australian children through vaccination
Hundreds of children in Western Australia (WA) are admitted to hospital each year with influenza. Preschool children and children with specific underlying conditions are at greatest risk of severe infection and death. WA is the only state with a publically-funded influenza vaccination program for all preschool children. Following vaccine-associated adverse events in 2010, uptake of childhood influenza vaccine has been poor.
Dr Blyth will undertake research to determine the effectiveness of influenza vaccine in West Australian children, explore the uptake in children with specific underlying conditions and describe patient and parental factors that influence acceptance of this important public health intervention.
Cumulatively rare diseases affect approximately 1 in 12 individuals which equates to 1.5 million Australians including over 400,000 children. This project provides a framework for the coordination of Western Australian rare disease (RD) research and clinical care that integrates with global initiatives.
It develops resources that: 1). define RD impact; 2). generate new functionality of existing RD registries; 3). facilitate modular generation of novel RD registries; 4). provide new objective tools, including 3D facial analysis, for RD diagnosis, description and treatment monitoring; 5). facilitate access to resources for individuals living with RD; and 6). synergistically contribute towards international RD efforts.
Evaluation of Haemophilus haemolyticus as a preventative therapy for ear disease
To investigate nasopharyngeal and gut microbiome profiles in ABC and CBC children regarding their dietary patterns
Improving gut biodiversity with soluble fibre in early life to prevent inflammatory disease - a pilot study to study effects on early immune development
Development of a new paradigm to accelerate translation of research discoveries into new treatments for patients
Developing a simple, rapid and accurate diagnostic test for neonatal sepsis
To identify epigenetic biomarkers of congenital heart defects in a family based epidemiology study
New uses for old drugs: repurposing treatments for childhood brain cancers
Identifying strategies for the prevention and treatment of rhinovirus-induced asthma
Metabolomics after preterm birth - A proof of concept study.
Imperial College London. $10,000.00.
University of Wisconsin, University of Southampton, University of Melbourne, University of Alberta, University of Cape Town, University of Sydney, Northwestern University, University of Marburg. $18,000.00.