School of Paediatrics and Child Health

Childhood Allergy and Immunology Research

Further Information

Our team

The Childhood Allergy and Immunology Research group (CAIR) is focused on allergic diseases affecting children and their prevention.

Research focus 

  • Identifying nutritional and environmental factors which influence the developing human immune system, particularly factors which predispose to allergic diseases (eczema, food allergy, hay fever and asthma in early childhood.
  • Clinical intervention studies for the prevention of allergic disease in childhood.


STEP Trial- Timing of egg introduction into the diets of infants to prevent egg allergy.
The STEP trial is to determine whether the incidence of egg allergy is reduced by early regular exposure to egg from around 6 months of age compared with the common practice of delaying egg introduction until 10 months of age.
STEP Trial [PDF, 326.9 KB]
Updated 31 Mar 2014

QUEST Trial - Egg in the diet of breastfeeding mothers to reduce egg allergy development in infants
The QUEST trial is a randomised controlled trial to investigate the effect of maternal dietary egg intake on egg levels in breast milk during the first six weeks of lacation.
QUEST Trial [PDF, 653.8 KB]
Updated 31 Mar 2014

VITAL Trial - Vitamin D supplementation to infants in the first 6 months of life to reduce eczema and food allergies
The VITAL trial is a double-blind randomised controlled trial to determine the effects of early postnatal (birth to 6 months of age) vitamin D supplementation on infant immune development.
VITAL Trial [PDF, 272.7 KB]
Updated 31 Mar 2014

Postgraduate research

Our postgraduates are currently conducting studies in:

  • Vitamin D supplementation and infant immune development. 
  • Maternal egg intake and egg detection in breast milk.
  • Nutritional epigenetics: the effect of nutrition in early life on differnetial gene expression analysis in children with allergic diseases.

School of Paediatrics and Child Health

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Last updated:
Tuesday, 15 April, 2014 10:17 AM