School of Paediatrics and Child Health

Aerosols Research Group

Further Information

A-Z Staff Research ProfilesFind out what our postgraduates are researching

Research Electives

We welcome medical students from other institutions to join us for elective terms of up to six weeks.

Contact

For more information on completing an elective, contact:

Team Members:

Areas of Research:

  • Optimisation of aerosol therapy for  children with asthma and cystic fibrosis
  • In vitro evaluation of particle size and drug delivery for development of therapeutic inhalers
  • Mechanistic pathways and lung health outcomes of inhaled particulate pollutants during gestation and early childhood

Research Overview:

Delivery of therapeutic aerosols to children, for the treatment of respiratory disease (primarily asthma and cystic fibrosis). Efficient delivery of inhaled drug therapy is problematic for paediatric respiratory patients, particularly in the infant and preschool years. Our research focuses on the evaluation of current commercial inhalational delivery systems and adaptation of commercial devices for use by children, and the development of new and innovative aerosol delivery devices primarily designed for the paediatric age group.

Development of an ex vivo model using a flow-volume simulator for prediction of total drug delivery and airway deposition

Effects of inhaled environmental particulate exposure on the development of asthma and atopy in vivo, and at the molecular level (through the development of physiological exposure systems for human bronchial epithelial cell cultures).

Contribution to international guidelines and consensus statements:

ERS/ISAM TASK FORCE CONSENSUS STATEMENT: Recommendations on what the pulmonary specialist should know about the new inhalation therapies. Eur Respir J 2011; 37: 1308-31.

ISAM STANDARDIZATION GUIDELINES: Standardization of Lung Imaging Techniques for Aerosol Deposition Assessment of Orally Inhaled Products. Journal of Aerosol Medicine and Pulmonary Drug Delivery Dec 2012; Volume 25, Supplement 1.


 

School of Paediatrics and Child Health

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Last updated:
Tuesday, 12 August, 2014 10:10 AM

http://www.paediatrics.uwa.edu.au/2583087